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Indication & Dosage |
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Oral |
DIARRHOEA OR DYSENTRY OF BACTERIAL, AMOEBIC OR MIXED ORIGIN |
Adult:
(Norfloxacin 400mg + Tinidazole 600mg tab) 1 tab b.i.d. for 5 days. |
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Precautions |
Moderate renal impairment, history of or susceptibility to seizures, alcohol intake. Ensure adequate hydration and urine output. |
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Potentially Life-threatening
Adverse Drug Reactions |
Nausea, vomiting, heartburn, metallic taste, headache, dizziness, depression, insomnia, rash, dry mouth, fever, arthralgia. Rarely eosinophilia, bone marrow depression. |
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Adverse Drug Reactions |
Rarely hypersensitivity reactions, facial and laryngeal oedema, hypotension, bronchospasm. |
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Interactions |
Antacids reduce absorption of norfloxacin from gut. Probenecid reduces urinary excretion of norfloxacin. |
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